Renaissance Quarterly is a comprehensive academic journal that focuses on interdisciplinary research during the Renaissance period. It covers a wide range of disciplinary fields, including but not limited to American studies, art and architecture, book history, classical traditions, comparative literature, etc., providing a platform for in-depth exploration of various aspects of research during the Renaissance period.

The journal has also shown a strong interest in digital humanities, which combines research methods from computer science and humanities, providing new perspectives and tools for traditional Renaissance studies. Emblem studies, as an important aspect of the Renaissance period, are also within the scope of magazine attention. It involves the design, symbolic meaning, and role of emblems in society and culture. It covers literary traditions from multiple countries, including English literature, French literature, Germanic literature, Hebraica (Hebrew literature), Hispanic literature, Italian literature, etc., showcasing the diversity and richness of Renaissance literature. At the same time, the journal also focuses on New Latin literature, which refers to the Latin literary works used during the Renaissance period.